Regotab® (Regorafenib) 40mg

Introduction to Stivarga (Regorafenib) 40mg 

Stivarga (Regorafenib) 40mg  is a targeted prescription medicine used in the treatment of certain advanced cancers, including colorectal cancer, gastrointestinal stromal tumors (GIST), and liver cancer. It belongs to a class of drugs known as multikinase inhibitors, which work by blocking multiple pathways involved in tumor growth.

Regotab® (Regorafenib) 40mg is classified under Prescription Medicines, Oncology Medicines, Targeted Cancer Therapies, and Oral Anticancer Drugs. It contains Regorafenib, which helps slow cancer progression by inhibiting tumor growth and blood vessel formation.

In some markets, Regotab® 40mg is available as a generic version of Regorafenib, offering similar therapeutic benefits when prescribed by a qualified healthcare professional.

What Is Stivarga (Regorafenib)? 

Stivarga is the original brand name for Regorafenib, an oral targeted therapy used to treat advanced cancers.

Regorafenib belongs to the class of multikinase inhibitors. These drugs block several protein kinases involved in tumor growth, angiogenesis, and cancer progression.

Generic versions such as Regotab® 40mg contain the same active ingredient and may be used based on physician recommendation and availability.

Drug Class and Mechanism of Action 

Regorafenib is classified as a multikinase inhibitor with strong antineoplastic properties.

How Regorafenib Works 

It works in several ways:

• Inhibits multiple kinases involved in tumor growth
• Blocks angiogenesis (formation of new blood vessels)
• Slows cancer cell proliferation

Through these mechanisms, Regorafenib helps control cancer progression.

How Stivarga Works in the Body 

Regorafenib targets multiple signaling pathways essential for tumor survival and growth.

Key Actions of Regorafenib 

• Reduces tumor blood supply
• Slows cancer growth
• Promotes cancer cell death

Generic versions like Regotab® provide similar therapeutic effects when used correctly.

Medical Uses of Stivarga (Regorafenib) 40mg 

Regotab® 40mg is used in advanced cancer treatment.

Regorafenib for Colorectal Cancer 

It is prescribed for metastatic colorectal cancer after other treatments have failed.

Potential Benefits 

• Slows disease progression
• Improves survival outcomes
• Provides an option after standard therapies

Regorafenib for Gastrointestinal Stromal Tumors (GIST) 

Used in patients with GIST who are resistant to other treatments.

Treatment Benefits 

• Controls tumor growth
• Offers additional treatment option

Regorafenib for Liver Cancer (Hepatocellular Carcinoma) 

Also used in advanced liver cancer cases.

Treatment Benefits 

• Helps slow cancer progression
• Improves disease management

Who Can Take Regotab® (Regorafenib) 40mg? 

This medicine must be used under specialist supervision.

Eligibility Criteria 

Patients may be prescribed Regorafenib if they:

• Have advanced colorectal cancer, GIST, or liver cancer
• Have not responded to previous treatments
• Are evaluated by an oncologist

Who Should Avoid Stivarga (Regorafenib) 40mg 

Regorafenib should NOT be used by:

• Patients with severe liver impairment
• Individuals with hypersensitivity to Regorafenib
• Pregnant or breastfeeding women

Stivarga (Regorafenib) 40mg Dosage and Administration 

Standard Dosage Guidelines 

Typical dosage recommendations include:

• Regotab® 40mg tablets taken once daily (usually multiple tablets as prescribed)
• Taken with a low-fat meal
• Given in treatment cycles (3 weeks on, 1 week off)

Dosage Adjustments 

Doctors may adjust the dose depending on:

• Liver function
• Side effects
• Treatment response

Side Effects of Regorafenib 40mg 

Like all cancer medicines, Regorafenib may cause side effects.

Common Side Effects 

• Fatigue
• Diarrhea
• Hand-foot skin reaction
• Loss of appetite

Serious Side Effects 

• Liver toxicity
• Severe bleeding
• High blood pressure
• Heart problems

Patients should report any unusual symptoms to their doctor immediately.

Storage:
Store below 30°C in a dry place, protected from moisture and light. Keep out of reach of children.

Frequently Asked Questions (FAQs) 

1. What is Regotab® (Regorafenib) 40mg used for? 

It is used to treat advanced colorectal cancer, GIST, and liver cancer.

2. Is Regorafenib chemotherapy? 

No. It is a targeted therapy (multikinase inhibitor), not traditional chemotherapy.

3. How should Regorafenib be taken? 

It is taken orally with a low-fat meal, usually in cycles.

4. Can Regorafenib be used long-term? 

Yes, depending on patient response and tolerance.

5. Is Regotab® the same as Stivarga? 

Yes. It contains Regorafenib, the same active ingredient as Stivarga.

6. Do I need a prescription for Regotab® 40mg? 

Yes. It is a prescription-only medicine.

7. Can pregnant women take Regorafenib? 

No. It may harm the unborn baby and should be avoided during pregnancy.

Medical Disclaimer 

Disclaimer:
The information provided is for educational purposes only and should not be considered medical advice. Regorafenib is a prescription-only medicine and must be used under the supervision of a qualified healthcare professional. Always consult your doctor before starting or stopping any medication.