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PULFIBR (Pirfenidone) 801mg

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Pulfibr 801mg contains Pirfenidone, an antifibrotic medicine used to treat idiopathic pulmonary fibrosis (IPF). It works by reducing lung scarring and slowing disease progression.

Field Details
Original Brand Esbriet
Generic Brand Pulfibr
Generic Name Pirfenidone 801mg
Pack Size 30 Tablets (Typical)
Use / Indications Idiopathic Pulmonary Fibrosis (IPF)
Manufacturer (Local Manufacturer – Bangladesh)
Status Prescription Only Medicine
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Introduction to Esbriet (Pirfenidone) 801mg 

Pulfibr (Pirfenidone) 801mg is a prescription medicine used in the treatment of idiopathic pulmonary fibrosis (IPF), a chronic lung disease that causes progressive scarring of lung tissue. It helps slow down the progression of fibrosis and improves lung function over time.

Pulfibr (Pirfenidone) 801mg is classified under Prescription Medicines, Respiratory Medicines, Antifibrotic Drugs, and Oral Pulmonary Therapies. It contains Pirfenidone, which works by reducing inflammation and fibrosis in lung tissues.

In some markets, Pulfibr 801mg is available as a local generic brand containing the same active ingredient Pirfenidone, offering similar therapeutic effects when prescribed by a qualified healthcare professional.

What Is Esbriet (Pirfenidone)? 

Esbriet is the original brand name for Pirfenidone, an oral medication widely used for the treatment of idiopathic pulmonary fibrosis.

Pirfenidone belongs to a class of medicines known as antifibrotic agents. These medicines help slow the progression of lung fibrosis and reduce inflammation.

Generic versions such as Pulfibr 801mg contain the same active compound and may be used depending on physician recommendation and regional availability.

Drug Class and Mechanism of Action 

Pirfenidone is classified as an antifibrotic and anti-inflammatory agent.

How Pirfenidone Works 

It works in several ways:

  • Reduces production of fibrotic growth factors
  • Inhibits collagen synthesis in lung tissue
  • Decreases inflammation in the lungs
  • Slows progression of lung scarring

Through these mechanisms, Pulfibr helps preserve lung function and delay disease progression.

How Esbriet Works in the Body 

In idiopathic pulmonary fibrosis, lung tissue becomes thick and scarred, making breathing difficult. Esbriet works by reducing fibrosis and inflammation, helping maintain lung capacity.

Key Actions of Pirfenidone 

  • Slows lung fibrosis progression
  • Improves breathing capacity
  • Reduces inflammatory response
  • Supports long-term lung function

Some generic versions such as Pulfibr deliver the same active compound, allowing similar antifibrotic therapy when prescribed appropriately.

Medical Uses of Esbriet (Pirfenidone) 801mg 

Esbriet for Idiopathic Pulmonary Fibrosis 

For patients with IPF, Esbriet helps slow disease progression and maintain lung function.

Potential Benefits 

  • Slower decline in lung capacity
  • Improved breathing function
  • Delayed disease progression

Who Can Take Pulfibr 801mg? 

Because Pirfenidone is a potent respiratory medicine, treatment should always be supervised by a healthcare provider.

Eligibility Criteria 

Patients may be prescribed Esbriet if they:

  • Are diagnosed with idiopathic pulmonary fibrosis
  • Require antifibrotic therapy
  • Can follow regular monitoring (liver function tests)

Who Should Avoid Esbriet (Pirfenidone) 801mg 

Esbriet should NOT be used by:

  • Patients with severe liver impairment
  • Individuals with hypersensitivity to Pirfenidone
  • Patients with severe kidney disease without supervision
  • Pregnant or breastfeeding women unless prescribed

Esbriet (Pirfenidone) 801mg Dosage and Administration 

Standard Dosage Guidelines 

Typical dosage recommendations include:

  • Esbriet 801mg taken three times daily (maintenance dose)
  • Dose is gradually increased during initiation phase
  • Taken with food to reduce side effects

Dosage Adjustments 

Doctors may adjust the dose depending on:

  • Liver function
  • Tolerability
  • Side effects

Side Effects of Esbriet 801mg 

Common Side Effects 

  • Nausea
  • Loss of appetite
  • Fatigue
  • Photosensitivity (sun sensitivity)

Serious Side Effects 

  • Liver toxicity
  • Severe skin reactions
  • Significant gastrointestinal issues
  • Weight loss

Patients should report any unusual symptoms to their doctor immediately.

Storage:
Store below 25°C in a cool, dry place, protected from moisture and sunlight. Keep out of reach of children.

Frequently Asked Questions (FAQs) 

1. Is Esbriet (Pirfenidone) 801mg safe for long-term use? 

Yes, it is commonly used long-term to slow disease progression under medical supervision.

2. Can I take Pulfibr 801mg daily? 

Yes, it is typically taken three times daily as prescribed.

3. Why should Pirfenidone be taken with food? 

Taking it with food helps reduce gastrointestinal side effects.

4. Can I stop taking Pulfibr suddenly? 

No, stopping abruptly may affect disease control. Always consult your doctor.

5. Is Pulfibr 801mg the same as Esbriet? 

Yes, both contain Pirfenidone as the active ingredient.

6. Can pregnant women take Pulfibr 801mg? 

It should only be used if prescribed by a doctor after evaluating risks and benefits.

7. Do I need a prescription to buy Pulfibr 801mg? 

Yes, it is a prescription-only medicine. For more info, contact on WhatsApp: https://wa.me/8801742433764

Medical Disclaimer 

Disclaimer:
The information provided on this page is for educational and informational purposes only and should not be considered medical advice. Pirfenidone is a prescription-only medication and must be used under the supervision of a qualified healthcare professional. Always consult your physician before starting, stopping, or changing any medication.

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