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PALBOKIN (Palbociclib) 125mg

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PALBOKIN 125mg contains Palbociclib, a CDK4/6 inhibitor used to treat HR-positive, HER2-negative breast cancer. It works by blocking cancer cell division and slowing tumor growth.

Field Details
Original Brand Ibrance
Generic Brand PALBOKIN 125mg
Generic Name Palbociclib
Pack Size 21 Capsules
Use / Indications HR+ HER2- Breast Cancer
Manufacturer Everest Pharmaceuticals Ltd. (Bangladesh)
Status Prescription Only Medicine
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Introduction to Ibrance (Palbociclib) 125mg 

Ibrance (Palbociclib) 125mg is a prescription medicine used for the treatment of hormone receptor-positive (HR+), HER2-negative advanced or metastatic breast cancer. It is commonly used in combination with endocrine therapy to improve treatment outcomes.

PALBOKIN 125mg is classified under Prescription Medicines, Oncology Medicines, Targeted Cancer Therapies, and Cyclin-Dependent Kinase (CDK) 4/6 Inhibitors. It contains Palbociclib, which works by blocking proteins involved in cancer cell division.

In many countries, Ibrance is the original brand containing the same active ingredient Palbociclib, offering similar therapeutic benefits when prescribed by a qualified healthcare professional.

What Is IIbrance (Palbociclib) 125mg? 

Ibrance is the brand name for Palbociclib, an oral targeted therapy used in breast cancer treatment.

Palbociclib belongs to a class of medicines known as CDK4/6 Inhibitors. These medicines help stop cancer cell growth by interfering with the cell cycle.

Generic versions such as PALBOKIN 125mg contain the same active compound and may be used depending on physician recommendation and availability.

Drug Class and Mechanism of Action 

Palbociclib is classified as a targeted anticancer agent with cell-cycle inhibition properties.

How Palbociclib Works 

It works in several ways:

  • Inhibits CDK4 and CDK6 enzymes
  • Blocks progression of cancer cells through the cell cycle
  • Slows tumor growth and proliferation

Through these mechanisms, Palbociclib helps control cancer progression.

How Ibrance Works in the Body 

Certain breast cancers depend on cell-cycle proteins for growth and survival.

Key Actions of Palbociclib 

  • Prevents cancer cell division
  • Enhances effectiveness of hormone therapy
  • Reduces tumor progression

PALBOKIN 125mg provides targeted treatment for HR+ breast cancer patients.

Medical Uses of Ibrance (Palbociclib) 125mg 

PALBOKIN 125mg is used in advanced breast cancer treatment.

HR-Positive, HER2-Negative Breast Cancer 

Used in combination with endocrine therapy such as aromatase inhibitors or fulvestrant.

Potential Benefits 

  • Improved progression-free survival
  • Delayed disease progression
  • Enhanced treatment response

Who Can Take PALBOKIN 125mg? 

This medicine should be used under oncology specialist supervision.

Eligibility Criteria 

Patients may be prescribed PALBOKIN if they:

  • Have HR-positive, HER2-negative breast cancer
  • Require combination targeted therapy
  • Are evaluated for treatment suitability

Who Should Avoid Ibrance (Palbociclib) 125mg 

This medicine should NOT be used by:

  • Patients with hypersensitivity to Palbociclib
  • Pregnant or breastfeeding women
  • Patients with severe uncontrolled infections

Ibrance (Palbociclib) 125mg Dosage and Administration 

Standard Dosage Guidelines 

Typical dosage includes:

  • PALBOKIN 125mg once daily
  • Taken for 21 days followed by 7 days off (28-day cycle)
  • Taken with food

Dosage Adjustments 

Doctors may adjust dosage depending on:

  • Blood counts (neutropenia)
  • Side effects
  • Patient tolerance

Side Effects of Ibrance (Palbociclib) 125mg

Like all cancer medicines, Palbociclib may cause side effects.

Common Side Effects 

  • Neutropenia (low white blood cells)
  • Fatigue
  • Nausea
  • Hair thinning

Serious Side Effects 

  • Severe infections
  • Lung inflammation (rare)
  • Blood disorders

Patients should report fever or signs of infection immediately.

Storage:
Store below 25°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.

Frequently Asked Questions (FAQs) 

1. Is Ibrance safe for long-term use? 

Yes, under oncologist supervision.

2. Is PALBOKIN 125mg chemotherapy? 

No. It is a targeted therapy.

3. Can it be used alone? 

It is usually used with hormone therapy.

4. Does it cure breast cancer? 

It helps control the disease but may not cure it.

5. Why are blood tests required? 

To monitor white blood cell counts and safety.

6. Is PALBOKIN the same as Ibrance? 

Yes. Both contain Palbociclib.

7. Do I need a prescription for PALBOKIN 125mg? 

Yes. It is a prescription-only oncology medicine.

Medical Disclaimer 

Disclaimer:
This content is for educational purposes only and should not be considered medical advice. Always consult a qualified healthcare professional before using this medication.

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